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In addition to its comedolytic, sebum-regulating, and anti-inflammatory properties, it appears capable of inhibiting extracellular matrix metalloproteinases and increasing collagen type I and III production.7 In a prospective study, 20 individuals were administered oral isotretinoin 20mg 3 times a week for 12 weeks

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Weight loss tends to occur gradually as the dose increases and the appetite-regulating effects become more pronounced

Mix 1 serving (5 g = 1 level scoop) product in 300 ml water

This is important because patients who dont lose weight on metformin are considered to be more resistant than others (and therefore more difficult to treat)